This meatloaf grilled cheese sandwich is the perfect fusion of two comfort food classics. Imagine the savory goodness of meatloaf combined with the melty, gooey delight of a grilled cheese sandwich. It's an easy and delicious way to use up leftover meatloaf, transforming it into a mouthwatering meal that everyone will love.
If you don't have leftover meatloaf at home, you might need to prepare some or purchase a pre-made one from the supermarket. Meatloaf is the star ingredient here, and its rich, savory flavor is essential to the dish. Everything else, like bread, cheddar cheese, and butter, is commonly found in most kitchens.
Ingredients For Meatloaf Grilled Cheese Sandwich
Bread: The base of the sandwich, providing structure and a crispy texture when grilled.
Cheddar cheese: Adds a rich, creamy, and tangy flavor that melts beautifully.
Meatloaf: The hearty, savory filling that makes this sandwich unique and satisfying.
Butter: Used to coat the bread, ensuring a golden, crispy exterior when grilled.
Technique Tip for This Recipe
To achieve a perfectly crispy and golden brown grilled cheese sandwich, ensure that the butter is evenly spread on the bread slices. This helps in achieving an even browning. Additionally, using a cast iron skillet can provide consistent heat distribution, which is crucial for melting the cheese thoroughly while preventing the bread from burning. For an extra layer of flavor, consider adding a thin spread of mustard or mayonnaise on the inside of the bread before assembling the sandwich.
Suggested Side Dishes
Alternative Ingredients
bread - Substitute with whole grain bread: Adds more fiber and nutrients.
bread - Substitute with sourdough bread: Provides a tangy flavor and chewy texture.
cheddar cheese - Substitute with mozzarella cheese: Offers a milder flavor and melts well.
cheddar cheese - Substitute with Swiss cheese: Adds a nutty flavor and creamy texture.
meatloaf - Substitute with veggie loaf: Suitable for vegetarians and provides a similar texture.
meatloaf - Substitute with turkey meatloaf: A leaner option with less fat.
softened butter - Substitute with olive oil: A healthier fat option with a rich flavor.
softened butter - Substitute with margarine: A dairy-free alternative that spreads easily.
Other Alternative Recipes Similar to This Sandwich
How to Store / Freeze This Sandwich
- Allow the meatloaf grilled cheese sandwich to cool completely before storing. This prevents condensation, which can make the bread soggy.
- Wrap each sandwich individually in plastic wrap or aluminum foil. This helps maintain freshness and prevents the sandwiches from sticking together.
- Place the wrapped sandwiches in an airtight container or zip-top bag. This provides an extra layer of protection against freezer burn.
- Label the container or bag with the date. This ensures you use the sandwiches within a reasonable timeframe, ideally within 1-2 months for the best quality.
- When ready to enjoy, thaw the sandwich in the refrigerator overnight. This gradual thawing helps maintain the texture of the bread and meatloaf.
- Reheat the sandwich in a skillet over medium heat. Cook until the bread is crispy and the cheese is melted, about 3-4 minutes per side. Alternatively, you can use a toaster oven or oven preheated to 350°F (175°C) for about 10-15 minutes.
- For an extra crispy texture, consider reheating the sandwich in a panini press or grill.
- Serve immediately with your favorite soup or salad for a complete meal.
How to Reheat Leftovers
Preheat your oven to 350°F. Wrap the meatloaf grilled cheese sandwich in aluminum foil to keep it from drying out. Place it on a baking sheet and heat for about 10-15 minutes or until the cheese is melted and the bread is crispy.
Use a skillet on medium heat. Place the sandwich in the skillet and cover it with a lid to help the cheese melt evenly. Heat for about 3-4 minutes on each side until the bread is golden brown and the meatloaf is warmed through.
For a quick method, use a microwave. Place the sandwich on a microwave-safe plate and cover it with a damp paper towel to prevent it from drying out. Microwave on medium power for about 1-2 minutes. Note that the bread might not be as crispy as other methods.
If you have an air fryer, preheat it to 350°F. Place the meatloaf grilled cheese sandwich in the basket and heat for about 5-7 minutes, flipping halfway through, until the cheese is melted and the bread is crispy.
Use a toaster oven set to 350°F. Place the sandwich on the rack and heat for about 10 minutes, or until the cheese is melted and the bread is crispy.
Best Tools for This Recipe
Skillet: A flat-bottomed pan used for cooking the sandwich on the stovetop.
Spatula: A tool for flipping the sandwich to ensure even cooking on both sides.
Butter knife: Used to spread the softened butter on the bread slices.
Cutting board: Provides a stable surface for slicing the meatloaf if needed.
Knife: For slicing the meatloaf into appropriate portions for the sandwich.
Plate: To assemble the sandwich before cooking and to serve it once done.
Measuring spoon: To measure the exact amount of butter needed for the recipe.
How to Save Time on Making This Sandwich
Pre-slice the meatloaf: Slice your meatloaf in advance and store it in the fridge. This saves time when assembling the sandwich.
Use pre-shredded cheese: Opt for pre-shredded cheddar cheese to cut down on prep time.
Pre-butter the bread: Butter your bread slices ahead of time and keep them in an airtight container.
Use a non-stick skillet: A non-stick skillet ensures even cooking and easy flipping, reducing the risk of burning.
Cook multiple sandwiches at once: If your skillet is large enough, cook two sandwiches simultaneously to save time.

Meatloaf Grilled Cheese Sandwich
Ingredients
Main Ingredients
- 4 slices Bread
- 2 slices Cheddar Cheese
- 2 slices Meatloaf
- 2 tablespoon Butter softened
Instructions
- Butter one side of each bread slice.
- Place one slice of bread, buttered side down, on the skillet.
- Add a slice of cheese, then meatloaf, and another slice of cheese.
- Top with the second slice of bread, buttered side up.
- Cook until golden brown and cheese is melted, about 4-5 minutes per side.
Nutritional Value
Keywords
Suggested Appetizers and Desserts for This Recipe
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